August 23 - Battle of Chaldiran. Selim I crushes the Persian army of Shah Ismail I.
September 5 - Selim captures the Persian capital of Tabriz without encountering any resistance, but is unable to hold it.
September 13 - September 14 - Battle of Marignano - The army of Francis I of France defeats the Swiss, thanks to the timely arrival of a Venetian army. Francis restores French control of Milan